Package: Ritable
Title: Pedigree-Based Heritability Estimation for Family Cohort Studies
Version: 0.2.1
Authors@R: c(
    person("Lucas", "França",
           email = "lucas.franca@northumbria.ac.uk",
           role = c("aut", "cre"),
           comment = c(ORCID = "0000-0003-0853-1319")),
    person("Mario", "Leocadio-Miguel",
           email = "mario.miguel@northumbria.ac.uk",
           role = "aut",
           comment = c(ORCID = "0000-0002-7248-3529"))
  )
Description: Provides profile-likelihood and general maximum-likelihood
        variance-components estimation of narrow-sense heritability
        (h2), household/common-environment effects (c2), and bivariate
        genetic and environmental correlations for quantitative traits
        in family cohort and twin studies. Additive genetic
        relationship matrices are built from pedigrees via 'kinship2',
        including monozygotic-twin relatedness overrides. Phenotypes
        are inverse-normal transformed internally. Likelihood-ratio
        tests use a one-sided chi-squared boundary correction
        equivalent to SOLAR Eclipse. Ninety-five percent confidence
        intervals are derived from the profile likelihood rather than
        Wald approximations. Batch estimation over many traits or trait
        pairs returns tidy data frames ready for downstream
        visualisation (forest plots, heatmaps) and includes
        Benjamini-Hochberg FDR correction for bivariate correlation
        batches.
License: MIT + file LICENSE
URL: https://r-itable.circadia-lab.uk,
        https://github.com/circadia-bio/R-itable
BugReports: https://github.com/circadia-bio/R-itable/issues
Encoding: UTF-8
Roxygen: list(markdown = TRUE)
Depends: R (>= 4.1.0)
Imports: kinship2, stats, utils, rlang, cli
Suggests: ggplot2, scales, pkgdown, testthat (>= 3.0.0), knitr,
        rmarkdown
Config/testthat/edition: 3
VignetteBuilder: knitr
Config/roxygen2/version: 8.0.0
Repository: https://circadia-bio.r-universe.dev
Date/Publication: 2026-08-27 00:54:08 UTC
RemoteUrl: https://github.com/circadia-bio/R-itable
RemoteRef: v0.2.1
RemoteSha: 7392a002f82b77bfaaf7c8f78b771fb00a54d9f0
NeedsCompilation: no
Packaged: 2026-10-26 06:54:12 UTC; root
Author: Lucas França [aut, cre] (ORCID:
    <https://orcid.org/0000-0003-0853-1319>),
  Mario Leocadio-Miguel [aut] (ORCID:
    <https://orcid.org/0000-0002-7248-3529>)
Maintainer: Lucas França <lucas.franca@northumbria.ac.uk>