Package: Ritable Title: Pedigree-Based Heritability Estimation for Family Cohort Studies Version: 0.1.0 Authors@R: c( person("Lucas", "França", email = "lucas.franca@northumbria.ac.uk", role = c("aut", "cre"), comment = c(ORCID = "0000-0003-0853-1319")), person("Mario", "Leocadio-Miguel", email = "mario.miguel@northumbria.ac.uk", role = "aut", comment = c(ORCID = "0000-0002-7248-3529")) ) Description: Provides profile-likelihood variance-components estimation of narrow-sense heritability (h2) for quantitative traits in family cohort studies. Additive genetic relationship matrices are built from pedigrees via 'kinship2'. Phenotypes are inverse-normal transformed internally. Likelihood-ratio tests use a one-sided chi-squared boundary correction equivalent to SOLAR Eclipse. Ninety-five percent confidence intervals are derived from the profile likelihood rather than Wald approximations. Batch estimation over many traits returns tidy data frames ready for downstream visualisation (forest plots, heatmaps). License: MIT + file LICENSE URL: https://r-itable.circadia-lab.uk, https://github.com/circadia-bio/R-itable BugReports: https://github.com/circadia-bio/R-itable/issues Encoding: UTF-8 Roxygen: list(markdown = TRUE) RoxygenNote: 7.3.2 Depends: R (>= 4.1.0) Imports: kinship2, stats, utils, rlang, cli Suggests: ggplot2, scales, pkgdown, testthat (>= 3.0.0), knitr, rmarkdown Config/testthat/edition: 3 VignetteBuilder: knitr Repository: https://circadia-bio.r-universe.dev Date/Publication: 2026-06-08 11:41:14 UTC RemoteUrl: https://github.com/circadia-bio/R-itable RemoteRef: v0.1.0 RemoteSha: 55f60f35e01e073a3384ba7e0a580db9c7f62218 NeedsCompilation: no Packaged: 2026-07-02 00:41:40 UTC; root Author: Lucas França [aut, cre] (ORCID: ), Mario Leocadio-Miguel [aut] (ORCID: ) Maintainer: Lucas França